Oxford Molecular Haematology

 

 Includes  National Haemoglobinopathy Reference Laboratory, Oxford Haemophilia

Centre and Haemato-oncology diagnostic Service

 

Address

Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX2 6TD

Contact 1

 Dr John Old (Scientific Director)

Contact 2

 Dr Shirley Henderson (Deputy Scientific Director)

Contact 3

 Dr Anna Schuh (Clinical Lead haemato-oncology and haemoglobinopathies )

Contact 4

Dr David Keeling/Dr Paul Giangrande (Clinical Leads Haemophilia)

Telephone 1

 01865 225298

Telephone 2

 01865 225329

Fax:

 01865 857095

Email 1

 john.old@orh.nhs.uk

Email 2

shirley.henderson@orh.nhs.uk  

Email 3

anna.schuh@orh.nhs.uk

Email 4

david.Keeling@ndm.ox.ac.uk/ paul.Giangrande@ndm.ox.ac.uk

Email 5

molhaem@orh.nhs.uk

Home page

 http://www.oxfordradcliffe.nhs.uk/forpatients/departments/labs/haematology/molhaem/molhaem.aspx

 

 

Services offered: 27/07/09

Disease

OMIM

UKGTN service*

(Approved, Pending, N/A)

 a-thalassaemia

 151623/191170

 approved

 b-thalassaemia

 141900, 187550, 603902, 604131

 approved

 db-thalassaemia

 142000, 604131

approved

 Abnormal Haemoglobins

142309, 141800, 141900, 142000, 142200, 142250

 approved

Hereditary Persistence of Fetal Haemoglobin

 142470, 141749

 approved

 Sickle cell disease

 603903

 approved

Acute Myeloid Leukaemia NPM1, FLT3 ITD & D835,

PML-RARA, AML-ETO,

CBF-βMYH11, C-KIT

 

164040,136351,

102578, 133425, 121360,  164920

 

Lymphoma (B cell and T cell clonality)

 147100, 186930, 186970, 186810

 

 Chronic Myeloid Leukaemia / Acute Lymphocytic Leukaemia BCR-ABL-multiplex

 

 

 608232

 

CML/ALL MRD monitoring

Q-PCR BCR-ABL

 

 608232

 

Myeloproliferative Disorders JAK2 V617F and JAK2 exon 12

 

 147796

 

Chronic Lymphocytic Leukaemia

IgVH Somatic Hypermutation

 

 

147100

 

 Chimerism (including leucocyte sub-sets)

 

 

 Haemophilia A

 306700

 

 Haemophilia B

 306900

 

 Von Willebrands Disease

 193400

 

Thrombophilia

Factor V Leiden

prothrombin 20210

 

612309

176930

 

 Factor V, VII, XIII and X

 612309, 227500, 134570, 227600

 

 Haemochromatosis

 HFE

 

235200

 

Juvenile Haemochromatosis Haemojuvelin, Hepcidin

 

602390

 

Haemochromatosis: Ferroportin Disease

Ferroportin

 

 

 

604653

 

*Services offered outside main commissioning area geographical

boundaries under the UK specialist Genetic Testing Network –

enquire to the laboratory on costs.